Conolidine’s analgesic consequences stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors in the central anxious system, conolidine modulates alternate molecular targets. A Science Advances analyze uncovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://thebookmarknight.com/story20414725/details-fiction-and-conolidin-to-replace-traditional-painkillers