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There is a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to decrease afferent soreness transmission and develop analgesia. As a result, drugs like clonidine that target alpha-two receptors can impact the transmission of agony. : connected to, served by, https://samuelm516qhw5.answerblogs.com/profile

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