Promethazine and daridorexant both of those raise sedation. Modify Therapy/Keep an eye on Closely. Coadministration will increase hazard of CNS despair, which may result in additive impairment of psychomotor effectiveness and bring about daytime impairment. promethazine decreases effects of pitolisant by Other (see remark). Stay away from or Use Alternate https://wockusa.com/product/yuflyma-adalimumab-aaty/